CYBA, cytochrome b-245 alpha chain, 1535

N. diseases: 177; N. variants: 23
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16966671
rs16966671
Entrez Id: 1535;4597
Gene Symbol: CYBA;MVD
CYBA;MVD
CUI: C0003165
Disease:
Anthracosis
0.010 GeneticVariation BEFREE No statistically significant difference was demonstrated in either the allele or genotype frequencies of the other four examined SNPs (rs13306296, rs4673, rs9932581, and rs16966671) between the CWP group and dust-exposed control group (all p > .05). 30654669 2019
dbSNP: rs7195830
rs7195830
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0003165
Disease:
Anthracosis
0.010 GeneticVariation BEFREE Using the additive and the dominant model, the CYBA SNP rs7195830 polymorphism also showed significant associations with CWP patients (p < .001, OR = 1.621; p = .003, OR = 1.711, respectively). 30654669 2019
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0740447
Disease:
Diabetic peripheral neuropathy
0.010 GeneticVariation BEFREE We showed a strong association of the CYBA polymorphism rs4673 with DPN in Slovak children and adolescents with T1D. 29924645 2018
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent
0.010 GeneticVariation BEFREE We showed a strong association of the CYBA polymorphism rs4673 with DPN in Slovak children and adolescents with T1D. 29924645 2018
dbSNP: rs1049254
rs1049254
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1863999
Disease:
Peroxisome Biogenesis Disorder, Complementation Group D
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs1049254
rs1049254
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1844376
Disease:
Granulomatous Disease, Chronic, X-Linked
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs1049254
rs1049254
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0018203
Disease:
Chronic granulomatous disease
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs1049255
rs1049255
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1844376
Disease:
Granulomatous Disease, Chronic, X-Linked
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs1049255
rs1049255
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0018203
Disease:
Chronic granulomatous disease
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs1049255
rs1049255
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1863999
Disease:
Peroxisome Biogenesis Disorder, Complementation Group D
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0018203
Disease:
Chronic granulomatous disease
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1863999
Disease:
Peroxisome Biogenesis Disorder, Complementation Group D
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1844376
Disease:
Granulomatous Disease, Chronic, X-Linked
0.010 GeneticVariation BEFREE The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD. 29132304 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0242379
Disease:
Malignant neoplasm of lung
0.010 GeneticVariation BEFREE <i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer. 28529598 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0596263
Disease:
Carcinogenesis
0.010 GeneticVariation BEFREE The roles of interleukin 8 (<i>IL8</i>) rs4073, nuclear factor kappa B (<i>NF</i>κ<i>B</i>) rs28362491, cytochrome b-245, alpha polypeptide (<i>CYBA</i>) rs4673, <i>NAD(P) H</i> dehydrogenase, quinone 1 (<i>NQO1</i>) rs1800566, nitric oxide synthase 2 and inducible (<i>NOS2</i>) rs2297518 polymorphisms in lung carcinogenesis were investigated. 28529598 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1306460
Disease:
Primary malignant neoplasm of lung
0.010 GeneticVariation BEFREE <i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer. 28529598 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0684249
Disease:
Carcinoma of lung
0.010 GeneticVariation BEFREE <i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer. 28529598 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1956346
Disease:
Coronary Artery Disease
0.030 GeneticVariation BEFREE Our data demonstrated that rs4673 transition may be involved in susceptibility to CAD and could be applied as a potential biomarker for this disease. 28474233 2017
dbSNP: rs1049255
rs1049255
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C1956346
Disease:
Coronary Artery Disease
0.010 GeneticVariation BEFREE But rs1049255 analysis demonstrated the absence of such an association with CAD. 28474233 2017
dbSNP: rs1049255
rs1049255
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0010068
Disease:
Coronary heart disease
0.010 GeneticVariation BEFREE Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis. 28474233 2017
dbSNP: rs1049255
rs1049255
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0010054
Disease:
Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis. 28474233 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0010068
Disease:
Coronary heart disease
0.010 GeneticVariation BEFREE Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis. 28474233 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0010054
Disease:
Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis. 28474233 2017
dbSNP: rs4673
rs4673
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C2919365
Disease:
Macroalbuminuric diabetic nephropathy
0.010 GeneticVariation BEFREE The p22phox C242T gene polymorphism (rs4673) may be linked to an increased susceptibility for overt diabetic nephropathy (ODN), but the study results are still inconclusive. 27926811 2017
dbSNP: rs3794624
rs3794624
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C0041296
Disease:
Tuberculosis
0.010 GeneticVariation BEFREE We found that the A allele of rs3794624 was a significant protective factor against tuberculosis</span> (GA vs. GG: OR = 0.74, 95% CI 0.57-0.96; GA vs. GG+AA: OR = 0.73, 95% CI 0.56-0.95), which was then replicated in the Chinese Tibetan population (GA vs. GG: OR = 0.68, 95% CI 0.51-0.92; AA+GA vs. GG: OR = 0.70, 95% CI 0.52-0.93; GA vs. GG+AA: OR = 0.68, 95% CI 0.51-0.92). 27901128 2016